National Database of the Virtual Institute of Cerebrovascular Diseases
- Conditions
- Cerebrovascular Disease
- Interventions
- Other: Collection of clinical, radiological, and biological data from patients' medical records
- Registration Number
- NCT05925699
- Brief Summary
The primary aim of the study is to develop a national registry of cerebrovascular diseases in order to define the subtypes of these diseases associated with a worse prognosis. Secondly, the study aims to find clinical, radiological, and biological markers capable tof predicting the outcome of cerebrovascular diseases and the onset of complications related to therapeutic procedures, and to calculate predictive prognostic scores composed of multiple variables.
Each participating center will collect clinical, radiological, and biological data from the medical records of the study participants. Patients included in the study will not undergo any additional medical procedures to those of normal clinical practice.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- All
- Target Recruitment
- 285600
- Diagnosis of cerebrovascular pathology defined according to the NINDS special report of 1990 as "all disorders in which there is an area of the brain transiently or permanently affected by ischemia or bleeding and/or in which one or more blood vessels of the brain are mainly altered by a pathological process", falling within the following codes of the International Classification of Diseases, 9th revision (ICD-9): ICD-9 430-438;
- Informed consent provided by the patient or his legal representative in the case of mental incapacity or by the parents/guardians in the case of minors.
- The patient, his legal representative in the case of mental incapacity or his parents/guardians in the case of minors clearly state their will to leave the study;
- Onset of cerebrovascular disease before January 1, 2016.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description All patients with new-onset cerebrovascular disease from January 1, 2016 to July 1, 2049 Collection of clinical, radiological, and biological data from patients' medical records -
- Primary Outcome Measures
Name Time Method Identification of subtypes of each cerebrovascular disease (ICD-9 430-438) associated with poor prognosis. July 1, 2023 - July 1, 2053 Identification and definition of the various subtypes of each cerebrovascular disease (International Classification of Diseases, 9th revision (ICD-9): ICD-9 430-438) associated with poor prognosis.
- Secondary Outcome Measures
Name Time Method Identification of radiological variables of each cerebrovascular disease able to predict the success of pharmacological or procedural therapies July 1, 2023 - July 1, 2053 Identification of radiological variables of each cerebrovascular disease able to predict the success of pharmacological or procedural therapies
Identification of neurophysiological variables of each cerebrovascular disease helping in differential diagnosis July 1, 2023 - July 1, 2053 Identification of neurophysiological variables and biomarkers of each cerebrovascular disease helping in differential diagnosis
Identification of clinical variables of each cerebrovascular disease capable of predicting the development of complications July 1, 2023 - July 1, 2053 Identification of clinical variables of each cerebrovascular disease capable of predicting the development of spontaneous complications or complications related to therapeutic procedures
Identification of radiological variables of each cerebrovascular disease helping in differential diagnosis July 1, 2023 - July 1, 2053 Identification of radiological variables of each cerebrovascular disease helping in differential diagnosis
Identification of neurophysiological variables of each cerebrovascular disease capable of predicting the development of complications July 1, 2023 - July 1, 2053 Identification of neurophysiological variables of each cerebrovascular disease capable of predicting the development of complications
Identification of radiological variables of each cerebrovascular disease capable of predicting the development of complications July 1, 2023 - July 1, 2053 Identification of radiological variables of each cerebrovascular disease capable of predicting the development of complications
Identification of biomarkers of each cerebrovascular disease helping in differential diagnosis July 1, 2023 - July 1, 2053 Identification of biomarkers of each cerebrovascular disease helping in differential diagnosis
Identification of clinical variables of each cerebrovascular disease correlated with its prognosis July 1, 2023 - July 1, 2053 Identification of the clinical variables of each cerebrovascular disease correlated with its prognosis
Identification of radiological variables of each cerebrovascular disease correlated with its prognosis July 1, 2023 - July 1, 2053 Identification of the radiological variables of each cerebrovascular disease correlated with its prognosis
Identification of neurophysiological variables of each cerebrovascular disease correlated with its prognosis July 1, 2023 - July 1, 2053 Identification of the neurophysiological variables of each cerebrovascular disease correlated with its prognosis
Identification of prognostic scores for each cerebrovascular disease July 1, 2023 - July 1, 2053 Identification of prognostic scores for each cerebrovascular disease, based on the combination of clinical, radiological, neurophysiological and biomarker variables
Identification of biomarkers of each cerebrovascular disease capable of predicting the development of complications July 1, 2023 - July 1, 2053 dentification of biomarkers of each cerebrovascular disease capable of predicting the development of complications
Identification of biomarkers of each cerebrovascular disease able to predict the success of pharmacological or procedural therapies July 1, 2023 - July 1, 2053 Identification of biomarkers of each cerebrovascular disease able to predict the success of pharmacological or procedural therapies
Identification of biomarkers of each cerebrovascular disease correlated with its prognosis July 1, 2023 - July 1, 2053 Identification of the biomarkers of each cerebrovascular disease correlated with its prognosis
Identification of clinical variables of each cerebrovascular disease helping in differential diagnosis July 1, 2023 - July 1, 2053 Identification of clinical variables of each cerebrovascular disease that help the clinician in early differential diagnosis
Identification of clinical variables of each cerebrovascular disease able to predict the success of pharmacological or procedural therapies July 1, 2023 - July 1, 2053 Identification of clinical variables of each cerebrovascular disease able to predict the success of pharmacological or procedural therapies
Identification of the clinical variables of each cerebrovascular disease useful for the personalization of the rehabilitation treatment and able to predict its functional outcome July 1, 2023 - July 1, 2053 Identification of the clinical variables of each cerebrovascular disease useful for the purpose of personalizing the rehabilitation treatment and able to predict the good functional outcome following the same rehabilitation treatments
Identification of the radiological variables of each cerebrovascular disease useful for the personalization of the rehabilitation treatment and able to predict its functional outcome July 1, 2023 - July 1, 2053 Identification of the radiological variables of each cerebrovascular disease useful for the personalization of the rehabilitation treatment and able to predict its functional outcome
Identification of the neurophysiological variables of each cerebrovascular disease useful for the personalization of the rehabilitation treatment and able to predict its functional outcome July 1, 2023 - July 1, 2053 Identification of the neurophysiological variables of each cerebrovascular disease useful for the personalization of the rehabilitation treatment and able to predict its functional outcome
Identification of the biomarkers of each cerebrovascular disease useful for the personalization of the rehabilitation treatment and able to predict its functional outcome July 1, 2023 - July 1, 2053 Identification of the biomarkers of each cerebrovascular disease useful for the personalization of the rehabilitation treatment and able to predict its functional outcome
Trial Locations
- Locations (1)
Fondazione Policlinico Universitario A. Gemelli IRCCS
🇮🇹Rome, Lazio, Italy