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Examination of influence of macronutrients composition on metabolic responses and arterial stiffness indexes during postprandial phase in lean and obese adults

Not Applicable
Completed
Conditions
lean and obese men.
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Registration Number
IRCT20190818044552N1
Lead Sponsor
Mashhad University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
Male
Target Recruitment
20
Inclusion Criteria

1. Aged 18-35 years 2. Lean adult include: with a BMI of 18.5-23.5 kg/m2, body fat percent between 12-22%, waist circumference <90cm; obese adult include: with a BMI>27.5 kg/m2, body fat percent > 27%, waist circumference >90cm. 3. Men 4. Signing the Written informed consent 5. willing to undertake required fasting durations

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Respiratory quotient. Timepoint: during 6 hours after test meal(half hours after meal and thus every 1hours until 6 hours). Method of measurement: indirect calorimetry.;Resting energy expenditure. Timepoint: during 6 hours after test meal(half hours after meal and thus every 1hours until 6 hours). Method of measurement: indirect calorimetry.;Total energy expenditure. Timepoint: during 6 hours after test meal(half hours after meal and thus every 1hours until 6 hours). Method of measurement: indirect calorimetry.;Diet induced thermogenesis. Timepoint: during 6 hours after test meal(half hours after meal and thus every 1hours until 6 hours). Method of measurement: indirect calorimetry.
Secondary Outcome Measures
NameTimeMethod
Pulse wave analysis. Timepoint: during 6 hours after test meal(half hours after meal and thus every 1hours until 6 hours). Method of measurement: tonometry.;Pulse wave velocity. Timepoint: during 6 hours after test meal(half hours after meal and thus every 1hours until 6 hours). Method of measurement: tonometry.;Blood sugar. Timepoint: during 6 hours after test meal(half hours after meal and thus every 1hours until 6 hours). Method of measurement: blood sample.;Insulin. Timepoint: during 6 hours after test meal(half hours after meal and thus every 1hours until 6 hours). Method of measurement: blood sample.;Lipid profile. Timepoint: during 6 hours after test meal(half hours after meal and thus every 1hours until 6 hours). Method of measurement: blood sample.
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