The impact of the macronutrient composition of a nutritional supplement on postprandial skeletal muscle protein synthesis in elderly.
Completed
- Conditions
- Sarcopenia
- Registration Number
- NL-OMON28946
- Lead Sponsor
- Danone Research – Centre for Specialised Nutrition
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
1. Age 65 y or older;
2. Male;
Exclusion Criteria
1. Indications related to inadequate glycemic control;
2. All co-morbidities interacting with mobility and/or muscle metabolism of the lower limbs;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mixed muscle protein fractional synthetic rate (FSR) [%/h].
- Secondary Outcome Measures
Name Time Method 1. Plasma leucine (Leumax [umol/L]; LeuiAUC [umol/(L*min)]);<br /><br>2. Plasma essential amino acids (EAAmax [umol/L]; EAAiAUC [umol/(L*min)]).