Evaluation of spasm of vessels in brain and its association with perioperative complications in patients undergoing surgery through nose using an endoscope using a transcranial doppler machine.
Not Applicable
- Conditions
- Health Condition 1: D352- Benign neoplasm of pituitary gland
- Registration Number
- CTRI/2023/07/054896
- Lead Sponsor
- DR NITHISHA ROY
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Consenting adult patients undergoing endoscopic trans nasal trans-sphenoidal pituitary invasive adenomas and non- invasive pituitary adenomas at Sree Chitra Tirunal Institute for Medical Sciences and Technology.
2. Age 18-60 years
3.ASA (American Society of Anaesthesiologists) class 1 and 2
4.GCS 15/15 prior to the surgery
Exclusion Criteria
1 .Patient refusal
2. Age less than 18 years and more than 60 years
3. Emergency surgery
4. Patients with previous history of stroke, transient ischemic attacks .
5. ASA class 3,4,5 patients
6.Patients with subarachnoid hemorrhage, vasospasm
7.Pregnant and lactating mothers
8.Transcranial surgery.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.To assess the utility of TCD in detecting vasospasm following endoscopic trans nasal surgeries for invasive pituitary adenoma & non-invasive pituitary adenoma. <br/ ><br>2. To clinically correlate between the TCD flow velocities & neurological complications like altered mental status, motor deficits, seizures, diabetes insipidus, CT scan evidence of infarcts or SAH. <br/ ><br>3 .To assess the risk factors for development of vasospam & neurological deficits in this subset of patients.Timepoint: TCD will be done before induction ,within 24hours of surgery,post operative day 3 & before discharge.
- Secondary Outcome Measures
Name Time Method Incidental findings are notified to surgeons & further management will be as per surgeons.Timepoint: During post operative days