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Clinical Trials/NCT00948129
NCT00948129
Completed
Not Applicable

Project ACTION: Adult Smoking Cessation Treatment Through Innovative Outreach to Neighborhoods

M.D. Anderson Cancer Center1 site in 1 country626 target enrollmentAugust 10, 2009

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Cigarette Smoker
Sponsor
M.D. Anderson Cancer Center
Enrollment
626
Locations
1
Primary Endpoint
Smoking abstinence rate
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

This trial studies how well a mobile smoking cessation intervention works in enhancing cancer outreach in low-income adult smokers. Mobile smoking cessation intervention may help smokers quit or cut back on smoking, and help increase the range of cancer prevention services provided to low-income adult smokers.

Detailed Description

PRIMARY OBJECTIVES: I. Compare the efficacy of three smoking cessation interventions targeting community based low-income uninsured and underinsured individuals in a group-randomized trial. II. Evaluate the role of quit motivation, nicotine withdrawal, risk perception, self-efficacy, social support, and negative affect as potential mediators of smoking abstinence. III. Compare the cost-effectiveness of the three treatment conditions. OUTLINE: Participants are randomized to 1 of 3 groups. GROUP I (STANDARD CARE): Participants undergo standard of care smoking cessation intervention consisting of brief advice to quit smoking, nicotine replacement therapy (NRT), and self-help written materials. GROUP II (ENHANCED CARE): Participants undergo standard of care smoking cessation intervention as in Group I and attend a health feedback counseling session at baseline. Participants also receive access to a smoking cessation hotline telephone number and supportive text messages daily for 12 weeks. GROUP III (INTENSIVE CARE): Participants undergo standard of care smoking cessation intervention as in Group I and attend a health feedback counseling session at baseline. Participants also receive access to a smoking cessation hotline telephone number, supportive text messages daily for 12 weeks, and a smoking cessation telephone call over 15 minutes weekly for 12 weeks. After completion of study, participants are followed up at 3, 6, and 12 months.

Registry
clinicaltrials.gov
Start Date
August 10, 2009
End Date
February 10, 2021
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Smoked at least 100 cigarettes in lifetime
  • English or Spanish speaking
  • Currently smoking at least 5 cigarettes a day, on average
  • Willing to set a quit smoking date within a week of the enrollment

Exclusion Criteria

  • Positive history of a medical condition that precludes use of the nicotine patch
  • Current use of nicotine replacement therapy (NRT)
  • Current use of other smoking cessation medications (e.g., Chantix or Zyban)
  • Pregnant or nursing
  • Enrolled in another smoking cessation study

Outcomes

Primary Outcomes

Smoking abstinence rate

Time Frame: At 12 months

The primary method of analysis will be mixed-model logistic regression.

Cost-effectiveness

Time Frame: At 12 months

Will perform an incremental cost-effectiveness analysis by comparing the expected economic costs and clinical benefits of the three strategies. Will create a decision-analytic model using TreeAge Pro 2007 software to conduct the incremental cost-effectiveness analysis.

Secondary Outcomes

  • Salivary cotinine levels(At 12 months)

Study Sites (1)

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