A randomised trial to determine the relative cost and effectiveness of pit and fissure sealants and fluoride varnish in preventing dental decay

Cardiff University (UK)0 个研究点目标入组 920 人开始时间: 2010年10月21日最近更新: 2019年8月26日

适应症

试验速览

•1. Year 2 children (aged 6 - 7 years) attending the schools participating in the current Cardiff and Vale University Health Board Fissure Sealant Programme
•2. Children with at least one-fully erupted caries-free first permanent molar

•Applied at screening:
•1. Children whose parents refuse consent
•2. Children who at the time of the clinical examination or PFS/FV placement refuse assent
•3. Children whose medical history precludes inclusion (i.e., those with a history of hospitalisation for asthma, or severe allergies, or allergy to Elastoplast)
•4. Children with ulcerative gingivitis or stomatitis
•5. Children with any facial or oral infections, e.g., cold sores
•6. Children with known sensitivity to colophony (kolophonium), or any of the product ingredients (e.g. methylacrylate in PFS)
•7. children with any abnormality of the lips, face or soft tissues of the mouth considered by the investigator to preclude acceptable application of either PFS or FV
•8. Children who are showing obvious signs of systemic illness (e.g. colds, 'flu, chicken pox, etc.,) should also be excluded on that day
•Applied at baseline examination:
•9. Children without at least one fully-erupted caries-free first permanent molar

发起方

Cardiff University (UK)