Podocyturia as Predictive Factor for Pre-eclampsia

Completed

• Conditions: Pre-Eclampsia

• Registration Number: NCT03316430
• Lead Sponsor: Hospices Civils de Lyon

Brief Summary

Pre-eclampsia is an hypertensive disorder appearing during pregnancy, inducing serious maternal, fetal and neonatal mortality and morbidity. Podocyn could be identified in the urine, before proteinuria, a key element in the diagnostic of pre-eclampsia. Preventive treatment using aspirin could be administrated in early pregnancy. We hypothesized that podocyturia could be an early indicator of preeclampsia. This is a prospective, non-interventional, monocentric study.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2017-10-17
• Study First Submitted QC: 2017-10-17
• Study First Posted: 2017-10-20
• Study Start: 2019-05-15
• Primary Completion: 2021-12-07
• Study Completion: 2021-12-07
• Status Verified: 2022-01
• Last Update Submitted: 2022-01-11
• Last Update Posted: 2022-01-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 1000

Inclusion Criteria

• women aged 18 years or more
• single pregnancy
• first planned prenatal visit before 16 weeks of gestation
• planned delivery at Hôpital Femme Mère Enfant in Lyon, France
• patient receiving information and non opposition to participate

Exclusion Criteria

• multiple pregnancy
• pregnancy stopped
• antecedent of nephropathy
• inability to understand information provided
• prisoner or under administrative supervision
• fetal malformation, chromosomal anomalies
• preterm delivery for other reason that any hypertensive disorder of pregnancy or Intrauterine growth restriction

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Occurrence of pre-eclampsia	At childbirth (around 8 months)	Occurrence of pre-eclampsia during pregnancy

Trial Locations

Locations (1)

Department of obstetrics, Femme Mère Enfant Hospital, Lyon, France; 🇫🇷 Bron, France