NCT02595632已完成不适用
Exhaled Breath Analysis by Secondary Electrospray Ionization (SESI-MS) in Healthy Controls
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 183
- 试验地点
- 1
- 主要终点
- The primary outcome will be the mass spectrometric exhaled breath pattern of healthy subjects.
研究概览
简要总结
The purpose of this study is to detect a specific profile of breath in healthy subjects by an untargeted metabolomic study using exhaled breath analysis by mass spectrometry.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Normal spirometry (forced expiratory volume in 1 second (FEV1) > 80%, forced vital capacity (FVC) > 80%, FEV1/FVC > 70%.).
- •Age between 18 and 90 years at study entry.
排除标准
- •Presence of an active malignancy.
- •Presence of any lung disease (e.g. asthma, chronic obstructive pulmonary disease (COPD), sarcoidosis)
- •Acute inflammatory disease (e.g. common cold) within the last 6 weeks.
- •Acute or chronic hepatic disease.
- •Renal failure or renal replacement therapy.
结局指标
主要结局
The primary outcome will be the mass spectrometric exhaled breath pattern of healthy subjects.
时间窗: 1 day, single measurement, no follow up
次要结局
未报告次要终点
研究者
研究点 (1)
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