Exhaled Breath Analysis in Human Subjects

Recruiting

• Conditions: Exhaled Breath Pattern After Medication Intake, in OSA Patients, or Other Pulmonary Diseases

• Registration Number: NCT05456009
• Lead Sponsor: University of Zurich

Brief Summary

Identification of exhaled breath pattern of human subjects

Detailed Description

Breath analysis with mass spectormetry as a non-invasive method to identfy exhaled breath patterns.

Study Timeline

• Study Start: 2019-02-19
• Study First Submitted: 2022-06-30
• Study First Submitted QC: 2022-07-07
• Study First Posted: 2022-07-13
• Status Verified: 2024-08
• Last Update Submitted: 2024-08-14
• Last Update Posted: 2024-08-15
• Primary Completion: 2026-03-01
• Study Completion: 2026-03-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 1500

Inclusion Criteria

• >= 18 years
• Informed consent

Exclusion Criteria

• specific exclusion criteria for different subgroups

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Exhaled breath pattern	baseline	mass spectrometric profile of exhaled breath pattern of human subjects

Secondary Outcome Measures

Name	Time	Method
Chemical structure of exhaled breath molecules	baseline	The identification of the chemical structure of exhaled breath molecules
Distinguish between disease	baseline	The use of a breath print to distinguish between disease and/or health state
Medication	baseline	Response to medication and toxicity as a function of blood/breath drug concentrations
Excretion of drugs	baseline	Correlation between lung function and the excretion of drugs in exhaled breath
Disease marker	baseline	The correlation of a distinct disease marker with a breath print or breath feature
Body fluids	baseline	The correlations of identified molecules in exhaled breath with body fluids
Health state	baseline	The correlation of breath prints to subjective health state and/or quality of life

Trial Locations

Locations (1)

University Hospital Zurich; 🇨🇭 Zürich, Zurich, Switzerland