Microvasculopathy in Cerebral Small Vessel Disease - Cerebral small vessel disease

Academisch Medisch Centrum0 个研究点目标入组 16 人开始时间: 待定最近更新: 2024年5月13日

适应症

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•Inclusion criteria cerebral large vessel disease group
•TIA or stroke patients with one of the following:
•-clinically demonstrated loss of sensibility
•-clinically demonstrated loss of motor function;and including one or more of the following:
•-hemianopsia
•-neglect;and a carotid stenosis of more than 70% at the ipsilateral side.
•Inclusion criteria cerebral small vessel disease group
•Patients with a clinically established lacunar syndrome (see appendix A) and lacunar infarcts and/or leukoaraiosis on CT.

•Exclusion criteria for both groups are:
•-Age of less than 18 years
•-Incapacitated subjects
•-A Modified Rankin Scale (MRS) >3
•-Diabetes Mellitus type I and II
•-Iodine allergy
•-Hyperthyroidism
•Exclusion criteria cerebral large vessel disease group
•-Lacunar infarcts and/or leukoaraiosis on CT
•-Indication of a cardiac source of intracranial embolism;Exclusion criteria cerebral small vessel disease group
•-Carotid stenosis of more than 30%
•-Intermittent claudication
•-Angina pectoris
•-Myocardial infarction
•-Radiologically demonstrated cortical infarction

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