NL-OMON42650
Completed
Not Applicable
On the origin of cerebral small vessel disease - On the origin of cerebral small vessel disease
eurologie0 sites50 target enrollmentTBD
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- cerebral small vessel disease
- Sponsor
- eurologie
- Enrollment
- 50
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Participants will be recruited from our ongoing RUNDMC study. The current proposal can be seen as an extension of the RUNDMC Study. Eligibility criteria for participation with the RUNDMC study included the presence of cerebral small vessel disease on neuroimaging (made because of symptoms of small vessel disease), age 50\-85 years.
- •For the current extension the following inclusion criteria will be added:;\- Above RUNDMC average progression of cerebral small vessel disease as assessed on sequential MRI scanning in 2006 and 2012\.
- •\- Have risk factors of progression
- •\- Hypertension
- •\- IADL \> 6 (functionally independent)
- •\- Being able to visit the research centre on a monthly basis
Exclusion Criteria
- •\- Atrial fibrillation
- •\- carotid artery stenosis \> 50%
- •\- Dementia
- •\- Mild cognitive impairment
- •\- Parkinsonism
- •\- Diabetes
Outcomes
Primary Outcomes
Not specified
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