NL-OMON51836
Recruiting
Not Applicable
INflammation and cerebral small vessel disease (INSVD) study - INSVD
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- immune system
- Sponsor
- Radboud Universitair Medisch Centrum
- Enrollment
- 100
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patient population
- •1\. Have given written informed consent to participate
- •2\. Be aged 40 years and over
- •3\. Have symptomatic cerebral small vessel disease defined as:
- •Clinically symptomatic lacunar infarct in presence of white matter
- •hyperintensities (Fazekas \>\=1\) on MRI
- •and/or symptoms of cognitive impairment due to small vessel disease (Fazekas
- •\>\= 1\) with lacunar infarct on MRI
- •and/or gait apraxia/motor impairment presumed due to small vessel disease
- •(Fazekas \>\= 1\) with lacunar infarct on MRI
Exclusion Criteria
- •Patient population
- •\- unable/unwilling to consent including lack of capacity to consent
- •\- vaccination or infection with fever in preceding month
- •\- any stroke cause other than SVD including:
- •o Cardioembolic source
- •o Carotid or vertebral stenosis \>50% measured on NASCET criteria
- •\- Myocardial infarction in past year
- •\- Vasculitis
- •\- any chronic disease that could lead to brain lesions mimicking SVD (for
- •example multiple sclerosis)
Outcomes
Primary Outcomes
Not specified
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