Effect of Ischemic Preconditioning on Relapse of Nonvalvular Atrial Fibrillation After Electrocardioversion

St. Josefs-Hospital Wiesbaden GmbH1 site in 1 country240 target enrollmentApril 1, 2022

ConditionsAtrial Fibrillation

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Atrial Fibrillation
Sponsor: St. Josefs-Hospital Wiesbaden GmbH
Enrollment: 240
Locations: 1
Primary Endpoint: Number of subjects with recurrence of atrial fibrillation 30 days after electrical cardioversion
Status: Completed
Last Updated: last year

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Remote ischemic preconditioning is one way to influence the success of therapy in cardiovascular patients. By means of remote ischemic preconditioning the incidence of atrial fibrillation after cardiac surgery was reduced by 54%. The investigators aim to investigate the effect of ischemic preconditioning in an easy-to-perform protocol with regard to the recurrence of atrial fibrillation after electrical cardioversion.

Registry

clinicaltrials.gov

Start Date

April 1, 2022

End Date

June 30, 2024

Last Updated

last year

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

St. Josefs-Hospital Wiesbaden GmbH

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Patients with paroxysmal or persistent atrial fibrillation who give written informed consent to participate in the study
•Age \> 18 years
•Consent capacity

Exclusion Criteria

•Age under 18 years
•Pregnancy
•Lack of consent capacity

Outcomes

Primary Outcomes

Number of subjects with recurrence of atrial fibrillation 30 days after electrical cardioversion

Time Frame: 30 days

Secondary Outcomes

Minimum energy required for successful electrocardioversion (in Joule)(30 days)
Cumulative energy applied for successfull electrocardioversion (in Joule)(30 days)
Number of patients with short-term cardioversion success(30 seconds)
Cumulative number of shocks delivered for successfull electrocardioversion(30 days)
Number of patients experiencing death from any cause, stroke /transient ischemic attack, relevant post-ECV arrhythmia and procedure-associated complications(30 days)