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临床试验/NCT05152706
NCT05152706已完成不适用

Parkinson´s Disease, Aerobic Exercise and Photobiomodulation: a Randomised Controlled Trial

University of Oviedo2 个研究点 分布在 1 个国家目标入组 72 人开始时间: 2021年1月10日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
72
试验地点
2
主要终点
MDS-UPDRS

研究概览

简要总结

The aim of the present study was to assess the effects of a combined therapy of aerobic exercise and transcranial photobiomodulation upon the cardinal motor sympomts of Parkinson´s disease of a group of Parkinson´s disease patients. It was hypothesized that aerobic exercise and transcranial photobiomodulation would yield significant benefits in the cardinal motor sympomts of the illness.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Factorial
主要目的
Treatment
盲法
None

入排标准

性别
All
接受健康志愿者

入选标准

  • Diagnosis with idiopathic PD and rated 1-2 on the Hoehn and Yahr Scale.
  • No type of dementia as assessed by the mini-mental state examination.
  • Able to stand for 2 min without assistance.
  • Able to walk 10 m without assistance.

排除标准

  • Individuals were excluded if they suffered a neurological disease other than PD, if the subject has an implant of any kind in the head (e.g., stent, clipped aneurysm, embolized arteriovenous malformation, implantable shunt - Hakim valve) or if they did not meet the eligibility criteria.

结局指标

主要结局

MDS-UPDRS

时间窗: 6 months

The motor portion of the Movement Disorder Society-Unified Parkinson´s (MDS-UPDRS, the minimum and maximum values are 0 and 72, respectively and the higher score, the worse patient condition)

次要结局

  • Static posturography(6 months)
  • TMWT(6 months)
  • Grip strength(6 months)
  • DASH(6 months)
  • TUG(6 months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Luis Santos

Principal Investigator

University of Oviedo

研究点 (2)

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