Parkinson´s Disease, Aerobic Exercise and Photobiomodulation

Not Applicable

Completed

• Conditions: Parkinson Disease

• Registration Number: NCT05152706
• Lead Sponsor: University of Oviedo

Brief Summary

The aim of the present study was to assess the effects of a combined therapy of aerobic exercise and transcranial photobiomodulation upon the cardinal motor sympomts of Parkinson´s disease of a group of Parkinson´s disease patients. It was hypothesized that aerobic exercise and transcranial photobiomodulation would yield significant benefits in the cardinal motor sympomts of the illness.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-01-10
• Study First Submitted: 2021-11-28
• Study First Submitted QC: 2021-11-28
• Study First Posted: 2021-12-10
• Primary Completion: 2024-06-30
• Study Completion: 2024-06-30
• Status Verified: 2024-12
• Last Update Submitted: 2024-12-03
• Last Update Posted: 2024-12-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 72

Inclusion Criteria

• Diagnosis with idiopathic PD and rated 1-2 on the Hoehn and Yahr Scale.
• No type of dementia as assessed by the mini-mental state examination.
• Able to stand for 2 min without assistance.
• Able to walk 10 m without assistance.

Exclusion Criteria

• Individuals were excluded if they suffered a neurological disease other than PD, if the subject has an implant of any kind in the head (e.g., stent, clipped aneurysm, embolized arteriovenous malformation, implantable shunt - Hakim valve) or if they did not meet the eligibility criteria.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: FACTORIAL

Primary Outcome Measures

Name	Time	Method
MDS-UPDRS	6 months	The motor portion of the Movement Disorder Society-Unified Parkinson´s (MDS-UPDRS, the minimum and maximum values are 0 and 72, respectively and the higher score, the worse patient condition)

Secondary Outcome Measures

Name	Time	Method
Static posturography	6 months	The centre of pressure (CoP) parameters (these CoP parameters; Length, in mm, Area in mm2 and Speed, Xspeed and Yspeed in m/s will be combined to report the static posturography)
TMWT	6 months	10 meters walking test (speed in seconds)
Grip strength	6 months	Grip strength in kg
DASH	6 months	The disabilities of the arm, shoulder and hand (DASH, the minimun and maximum values are 0 and 190, respectively and the higher score, the worse patient condition)
TUG	6 months	Time up Go Test (speed in seconds)

Trial Locations

Locations (1)

Department of Physical Education and Sport, University of León; 🇪🇸 León, Castilla y León, Spain