Evaluation of Efficacy, Safety and Tolerability of Targretin Capsules in Patients With Advanced or Metastatic Non-small Cell Lung Cancer
- Conditions
- Non-small Cell Lung Cancer
- Registration Number
- NCT00050973
- Lead Sponsor
- Eisai Inc.
- Brief Summary
This study evaluates the use of Targretin capsules (bexarotene) in combination with standard chemotherapy for the treatment of metastatic Non-Small Cell Lung Cancer (NSCLC) in patients who have not yet received chemotherapy for their lung cancer.
- Detailed Description
This study evaluates the use of Targretin capsules (bexarotene) in combination with Cisplatin and Vinorelbine for the treatment of metastatic non-small cell lung cancer in patients who have not yet received chemotherapy for their lung cancer. Every patient receives a platinum-containing chemotherapy every four weeks for at least four chemotherapy cycles (approximately four months). Half of the patients are randomly assigned to receive Targretin capsules once daily in addition to the chemotherapy. The other half is randomized to receive a standard platinum-containing chemotherapy without Targretin capsules.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 623
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (77)
Brookwood Medical Center
🇺🇸Birmingham, Alabama, United States
Southern Arizona VA Healthcare System
🇺🇸Tucson, Arizona, United States
Arroyo Research Inc.
🇺🇸Pasadena, California, United States
Desert Hematology-Oncology Medical Group, Inc.
🇺🇸Rancho Mirage, California, United States
University of Florida
🇺🇸Gainsville, Florida, United States
New Hope Cancer Center
🇺🇸Hudson, Florida, United States
Veterans Affairs Medical Center
🇺🇸Miami, Florida, United States
Bay Area Cancer Consultants
🇺🇸Palm Harbor, Florida, United States
Northwest Medical Specialists
🇺🇸Arlington Heights, Illinois, United States
Jayne Gurtler, M.D., APMC
🇺🇸Metairie, Louisiana, United States
Scroll for more (67 remaining)Brookwood Medical Center🇺🇸Birmingham, Alabama, United States