0.15 mg Spinal Morphine vs. no Treatment for Morphine Requirement After VATs.

Phase 4

• Conditions: Postoperative Pain
• Interventions: Drug: Spinal morphine

• Registration Number: NCT01979354
• Lead Sponsor: Mahidol University

Brief Summary

Postoperative pain after Video-assisted Thoracoscopic Surgery (VAT) is still debating. Therefore the investigators conduct a study comparing 0.15 mg spinal morphine and control group in term of analgesia.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2013-11-02
• Study First Submitted QC: 2013-11-07
• Study First Posted: 2013-11-08
• Study Start: 2014-02
• Status Verified: 2015-11
• Last Update Submitted: 2015-11-09
• Last Update Posted: 2015-11-10
• Primary Completion: 2016-12
• Study Completion: 2016-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Age 18 year or over
• Patient ASA physical status I-III.
• Scheduled for video-assisted thoracoscopic lobectomy or blebectomy with pleurectomy or pleural abrasion
• Can operate a patient-controlled analgesia (PCA) device.

Exclusion Criteria

• Known hypersensitivity to morphine
• History of bleeding tendency.
• Known case of infection at the back
• Patient refuse for spinal anesthesia
• History of cerebrovascular disease.
• Need mechanical ventilatory support during postoperative period

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Spinal morphine	Spinal morphine	0.15 mg spinal morphine

Primary Outcome Measures

Name	Time	Method
Total morphine requirement in 48 hours	48 hours

Secondary Outcome Measures

Name	Time	Method
Pain	48 hours

Trial Locations

Locations (1)

Mahidol University; 🇹🇭 Bangkok, Thailand