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Low-dose Spinal Morphine for Post-Thoracotomy Pain After Video-Assisted Thoracoscopic Surgery

Phase 4
Completed
Conditions
Video-assisted Thoracoscopic Surgery
Interventions
Other: control
Registration Number
NCT01917448
Lead Sponsor
Mahidol University
Brief Summary

One-thirds of patients underwent video-assisted thorascopic surgery still have severe pain. Therefore we want to demonstrate weather 0.15 mg spinal morphine would reduce 24 hour postoperative requirement comparing to control group.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
36
Inclusion Criteria
  • ASA (American Society of Anesthesiologist) physical status I to III,
  • Undergoing elective video-assisted thoracoscopic surgery at Siriraj and Thammasart Hospitals
  • capable of using a patient-controlled analgesia (PCA) machine
  • understanding the numeric rating scale (NRS) score for pain assessment.
Exclusion Criteria
  • history of allergy to the study drugs
  • bleeding disorder
  • infection of the back
  • refusing spinal anesthesia
  • history of cerebrovascular disease
  • using postoperative ventilator support were excluded

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
ControlcontrolThe skin will be injected with local anesthetic without spinal block
Spinal morphineMorphine0.15 mg spinal morphine
Primary Outcome Measures
NameTimeMethod
Total post-operative morphine requirement.48 hours
Secondary Outcome Measures
NameTimeMethod
Pain after surgery48 hour

Trial Locations

Locations (1)

Faculty of Medicine, Siriraj Hospital, mahidol University

🇹🇭

Bangkok, Thailand

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