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Clinical Trials/NCT03272113
NCT03272113
Completed
Not Applicable

Promoting Smoking Cessation During Pregnancy: a Combined Feasibility and Pilot Trial of a Theory-based Intervention Using Narrative, Images and Embedded Behaviour Change Techniques, Delivered Via Text-messaging

University of Stirling2 sites in 1 country28 target enrollmentDecember 5, 2017

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Smoking Cessation
Sponsor
University of Stirling
Enrollment
28
Locations
2
Primary Endpoint
Recruitment rate
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

The aim of this study is to investigate the feasibility and likelihood of success of a narrative and image-based intervention, administered via text messages, for smoking cessation in pregnant women, prior to undertaking a large scale trial of its effectiveness. A feasibility and pilot trial will be undertaking involving 70 pregnant women who smoke in two NHS Boards.

Detailed Description

Smoking during pregnancy carries serious risks to mother and infant health. More babies whose mothers smoke are stillborn or die within the first year of life. Smoking during pregnancy results in increased rates of intrauterine growth retardation, preterm birth, and babies' longer-term risk of developing heart disease and diabetes. Pregnant women who smoke are more likely to experience miscarriage, placental abruption, pregnancy-induced hypertension and later conditions such as lung cancer and heart disease. Reduction in smoking in pregnancy has been a long standing health policy target however there is limited evidence of effectiveness of many smoking cessation interventions and their uptake is generally low. We have developed, and carried out initial testing of an intervention to support smoking cessation in pregnant women using narrative, story-telling delivered via automated text-messages. The intervention aims to alter women's perceptions of risk, social norms, outcomes and self-efficacy using three key elements. 1. a narrative story of a fictional young pregnant woman 'Megan' trying to stop smoking by overcoming a series of commonplace barriers. 2) images showing the size of their fetus and its stage of development 3) an interactive 'help' function to receive a supportive, tailored response. Behaviour change techniques for smoking cessation in pregnancy are embedded in the intervention. A randomised controlled trial is required to test the effectiveness of the intervention in reducing smoking in pregnancy. The aim of this study is to investigate the feasibility and likelihood of success of the narrative and image-based intervention for smoking cessation in pregnant women. If successful the intervention will be tested in a full-scale (Phase III) multi centre randomised controlled trial. Objectives: 1. To assess acceptability and willingness to be randomised to the narrative and image based intervention or usual care. 2. To assess and compare the feasibility of recruitment strategies, the level of participants' retention in the study and engagement with the intervention. 3. To assess the acceptability and likely impact of the intervention among pregnant smokers. 4. To estimate the required sample size for a full trial.

Registry
clinicaltrials.gov
Start Date
December 5, 2017
End Date
August 31, 2019
Last Updated
6 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Helen Cheyne

Professor of Maternal and Child Health Research

University of Stirling

Eligibility Criteria

Inclusion Criteria

  • Women 16 years of age or over,
  • Live within the catchment areas of study sites,
  • Up to and including 14 weeks of pregnancy,
  • Current smoker,
  • Own or regularly use a mobile phone with media capability,
  • Understand written English,
  • Able to give informed consent.

Exclusion Criteria

  • Women who do not currently smoke,
  • Live outside the catchment areas of study sites,
  • Over 14 weeks of pregnancy,
  • Do not use or have access to a mobile phone with media capability,
  • Cannot understand written English,
  • Not able to give informed consent,
  • Already enrolled in an alternative formal smoking cessation trial at the time of referral to the study.

Outcomes

Primary Outcomes

Recruitment rate

Time Frame: 23 months

Progression to a full trial will require recruitment ≥50% of women who give permission to have their details passed to the research team (i.e. those who express initial interest in the study).

Drop out rate

Time Frame: 23 months

Progression to a full trial will require \<30% dropout

Direction of effect

Time Frame: 23 months

Progression to a full trial will require direction of effect on smoking cessation rate in favour of the intervention.

Secondary Outcomes

  • Engagement(23 months)
  • Acceptability(23 months)

Study Sites (2)

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