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Clinical Trials/NCT05355012
NCT05355012
Recruiting
Not Applicable

Organization of Smoking Cessation in Pregnant Women: Study of the Effectiveness, Transferability, Barriers and Facilitators of the Implementation of the 5A Strategy in French Context. A Cluster Randomized Controlled Trial in New Aquitaine.

University Hospital, Bordeaux1 site in 1 country4,505 target enrollmentOctober 3, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Smoking Cessation
Sponsor
University Hospital, Bordeaux
Enrollment
4505
Locations
1
Primary Endpoint
Tobacco abstinence at delivery
Status
Recruiting
Last Updated
2 years ago

Overview

Brief Summary

The investigators are conducting a pragmatic cluster randomized trial in stepped-wedge of which objectives are to evaluate the effectiveness and the conditions of effectiveness of an organizational strategy for smoking cessation - 5A-QUIT-N - among pregnant women in New Aquitaine (NA), by using and optimizing existing resources

Detailed Description

In France, in 2016, 16.6% of pregnant women were smokers, the highest levels among European countries. Pregnancy is considered a teachable moment for smoking cessation. There are many tools, interventions and programs to reduce the smoking habits of pregnant women. The challenge is therefore not to propose new interventions but to understand what is hindering the implementation of existing interventions and proposing corrective measures. In this context, the scientific literature shows that interventions for smoking pregnant women only seem effective when based on a comprehensive approach that combines multiple interventions. In particular, interventions based on the 5A's model (Ask, Advise, Assess, Assist, Arrange) are largely recommended and have shown their effectiveness abroad. Factors facilitating or hindering the implementation of such strategies are mainly organizational. As organizations are context-dependent by nature, considering the generalization of such strategies in France therefore requires adapting them to the French health system and evaluating them in context, in a pragmatic approach, inserted into routine care and using the tools, procedures and existing organizations in the territories.

Registry
clinicaltrials.gov
Start Date
October 3, 2022
End Date
May 31, 2026
Last Updated
2 years ago
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Sponsor
University Hospital, Bordeaux
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Tobacco abstinence at delivery

Time Frame: At delivery (smoking status of the previous 7 days)

The point prevalence of abstinence at delivery, which is the proportion of women reporting abstinence from smoking for at least 7 days at delivery. This criterion is well documented in the literature assessing tobacco use. It has the advantage of detecting the delayed effects of an intervention and can be easily extrapolated.

Secondary Outcomes

  • Sustainability of professional practices(18 months from the deployment of the intervention)
  • Postpartum relapse rate at 6 months(At 6 months postpartum)
  • Postpartum relapse rate at 12 months(At 12 months postpartum)
  • Continued abstinence(6 months and 1 year after delivery)
  • Attempts to quit smoking(1 to 3 days after delivery)
  • Birth weight(At baby birth, up to 3 days after delivery)
  • Conditions of transferability(Through study completion, an average of 3 years)
  • Average number of cigarettes smoked at inclusion(At inclusion)
  • Gestational age(At baby birth, up to 3 days after delivery)
  • Average number of cigarettes smoked at postpartum(6 months and 1 year after delivery)
  • Attempts to reduce tobacco consumption(1 to 3 days after delivery)
  • Continuous abstinence(1 to 3 days after delivery)
  • Implementation of intervention(Through study completion, an average of 3 years)
  • Sustainability of the impact on health(18 months from the deployment of the intervention)
  • Viability(Through study completion, an average of 3 years)

Study Sites (1)

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