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Clinical Trials/NCT03442530
NCT03442530
Completed
Not Applicable

Tobacco Use in Pregnancy Intervention for Cessation

Kristin Ashford1 site in 1 country66 target enrollmentJanuary 22, 2018
ConditionsPregnancy

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Pregnancy
Sponsor
Kristin Ashford
Enrollment
66
Locations
1
Primary Endpoint
Smoking cessation
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

The proposed project will test the effectiveness of the novel delivery of an established tobacco cessation treatment among pregnant women in Kentucky. Tobacco use during pregnancy is one of the most modifiable risk factors associated with poor birth and maternal outcomes and yet smoking prevalence among pregnant women in Kentucky is among the highest in the county and estimated to be twice that of the national average, with no meaningful declines observed in twenty years.

Detailed Description

The purpose of this pilot project is to test effectiveness of a tobacco-treatment cessation intervention (American College of Obstetricians and Gynecologists (ACOG) 5 A's) through use of a non-physician healthcare champion from within the clinic's existing infrastructure. This Tobacco use in Pregnancy Intervention for Cessation (ToPIC) will involve training the identified healthcare provider to become a Certified Tobacco Treatment Specialist (CTTS) and to administer the 5 A's to pregnant Medicaid patients receiving prenatal care through two high-volume Kentucky obstetrics clinics. This trial will provide evidence to evaluate this approach to delivering an established intervention in clinical practice. The Investigators propose to test the effectiveness of the clinical intervention by using a two-armed cluster randomized controlled design. Eligible participants will be randomized to the intervention (ToPIC) or standard of care for smoking cessation in pregnancy. This pilot project will gather quantitative and qualitative data for a mixed-method, multi-stakeholder process evaluation of intervention training and delivery. Furthermore, the Investigators' use of Medicaid claims data to examine healthcare utilization outside of maternal and infant well-care visits will enhance understanding of the strengths and limitations of these data for future evaluations. This study has the potential to significantly impact the most vulnerable in Kentucky, where rates of tobacco use among pregnant women are among the highest in the nation.

Registry
clinicaltrials.gov
Start Date
January 22, 2018
End Date
February 15, 2019
Last Updated
6 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Sponsor
Kristin Ashford
Responsible Party
Sponsor Investigator
Principal Investigator

Kristin Ashford

Associate Dean of Undergraduate Faculty Affairs, University of Kentucky College of Nursing

University of Kentucky

Eligibility Criteria

Inclusion Criteria

  • tobacco user
  • able to read and write English
  • Medicaid eligible

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Smoking cessation

Time Frame: Baseline to third trimester

Change in urine cotinine level

Secondary Outcomes

  • Smoking cessation after delivery(Prior to delivery hospitalization discharge, estimated 3 days)
  • Infant birth weight(At time of delivery)
  • Health care utilization outside of well-visits(Birth to 6 months)
  • Number of cigarettes per day(Baseline to third trimester)
  • Gestational age(At time of delivery)

Study Sites (1)

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