Medial arterial calcification in patients with hemophilia
Completed
- Conditions
- Medial arterial calcification - calcification in the middle layer of the vascular wall10003216
- Registration Number
- NL-OMON44851
- Lead Sponsor
- niversitair Medisch Centrum Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
Patients:
Hemophilia A or B
Males, age * 18 years
Written informed consent for study participation;Controls:
Males, age * 18 years
Written informed consent for study participation
Exclusion Criteria
Patients:
History of peripheral artery occlusive disease.
Patients with ESRD , defined as eGFR < 60 ml/ min, calculated according to the Modi*cation of Diet in Renal Disease formula.
Patients with diabetes mellitus.;Controls:
History of peripheral artery occlusive disease.
History of renal insufficiency
History of diabetes mellitus
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The main study parameter is the ABI in patients with haemophilia as compared to<br /><br>control subjects.</p><br>
- Secondary Outcome Measures
Name Time Method <p>Not applicable</p><br>