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Medial arterial calcification in patients with haemophilia

Recruiting
Conditions
Hemophilia patientsVascular calcificationAnkle brachial index
Registration Number
NL-OMON20634
Lead Sponsor
niversitair medisch centrum Groningen
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
50
Inclusion Criteria

Hemophilia A or B

- Males, adults

Exclusion Criteria

- History of peripheral artery occlusive disease.

- History of ESRD , defined as eGFR < 60 ml/ min, calculated according to the Modification of Diet in Renal Disease formula.

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Ankel brachial index<br /><br>Toe brachial index
Secondary Outcome Measures
NameTimeMethod
- Blood pressure, weight, height, waist circumference <br /><br>- Data related to cardiovascular risk factors will be obtained by a standardised questionnaire.<br /> <br>- Severity of haemophilia, bleeding events. <br /><br>-Total cholesterol, LDL-, and HDL- cholesterol, triglycerides, glucose, HbA1c, creatinine, alkaline phosphatase, calcium, phosphate, albumin.
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