Is echocardiographic Doppler measurement of mitral inflow and venous pulmonary flow more reliably reflects actual left atrial pressures than PAOP measurements in the presence of impaired myocardial function or myocardial hypertrophy?
- Conditions
- coronary artery bypass grafting1001928010007593
- Registration Number
- NL-OMON33638
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 10
Inclusion Criteria
1) Patients scheduled to undergo elective aortic valve replacement due to significant aortic valve stenosis, defined by an aortic valve area of <1 cm², and concordingly left ventricular hypertrophy, defined by an interventricular septum thickness > 11 mm on echocardiography.
2) Patients undergoing coronary artery bypass surgery suffering from compromised left ventricular function, defined by a left ventricular ejection fraction of < 45% on preoperative echocardiography
3) written informed consent
Exclusion Criteria
Preoperative exclusion criteria include: intracardiac shunts, more than trivial regurge of the mitral valve or tricuspid valve and patients with any degree of mitral valve stenosis.
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Comparison of left atrium pressure measurement with pulmonary artery occlusion<br /><br>pressure and echo-Doppler derived variables (pulsed wave Doppler of mitral<br /><br>inflow, tissue Doppler imaging of the mitral annulus, pulsed wave Doppler of<br /><br>pulmonary vein flow en colour M-mode of mitral inflow).</p><br>
- Secondary Outcome Measures
Name Time Method <p>not applicable</p><br>