Intra-articular platelet-rich plasma vs corticosteroids in the treatment of moderate knee osteoarthritis

Phase 1

Completed

• Conditions: Knee osteoarthritis; Musculoskeletal Diseases

• Registration Number: ISRCTN46024618
• Lead Sponsor: ORTO KLINIKA

Brief Summary

2020 results in https://pubmed.ncbi.nlm.nih.gov/32650801/ (added 13/07/2020)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2017-05-30
• Study Start: 2019-09-16
• Last Update Posted: 27 July 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

1. Patients older than 55 years with a history of chronic pain, swelling and/or reduced range of motion in the knee joint
2. Clinical and radiological confirmation of OA of the knee (Kellgren – Lawrence KL grades II-III) was verified by assessing X-Ray images in anteroposterior and lateral projections

Exclusion Criteria

1. Posttraumatic knee
2. Pregnancy, breastfeeding
3. Oncological diseases
4. Endocrine diseases (gout, diabetes)
5. Autoimmune diseases (rheumatoid arthritis)
6. Acute/chronic infectious disease, blood clotting disorders (thrombocytopenia, coagulopathy)
7. Previous interventions on the knee joint (i.e. punctures, blockades, arthroscopy)
8. Received consistent hormonal therapy or non-steroidal anti-inflammatory drugs (NSAIDs) within 10 days prior to the intervention

Study & Design

• Study Type: Interventional
• Study Design: Not specified