An Diagnostic Cohort on AQP4-Immunoglobulin G Detection Kit
Completed
- Conditions
- Neuromyelitis Optica Spectrum Disorders
- Registration Number
- NCT04388072
- Brief Summary
The diagnostic cohort study could will be use to verify the clinical performance of the AQP4 -immunoglobulin G detection kit and whether it has a good correlation with the clinical diagnosis results. The applicability and accuracy of the kit in clinical diagnosis will be verified according to the measured data.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 200
Inclusion Criteria
- The patients who were diagnosed with NMOSD , and the cell-based assay was used to determine the AQP4-IgG-seropositive patients;
- AQP4-IgG is negative in health people with age and sex matching and determined by cell-based assay;
- Female or male, age 14-80;
- Patients or authorized family members volunteered to participate in this study and signed informed consent.
Exclusion Criteria
- Patients with coagulation disorders;
- Infection-related encephalitis;
- Immune-related encephalitis;
- A patient with severe mental illness who cannot cooperate clinically;
- A patient with severe jaundice.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method results of AQP4 -immunoglobulin G detection kit through study completion, an average of 6 months The Serum test results of participants using AQP4 -immunoglobulin G detection kit
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (2)
Department of Neurology,First Affiliated Hospital of Fujian Medical University
🇨🇳Fuzhou, Fujian, China
Third Affiliated Hospital of Sun Yat-sen University
🇨🇳Guangzhou, China