Genome-wide Association Study of Development of Collateral Circulation for Patients With Coronary or Peripheral Artery Disease

Recruiting

• Conditions: Peripheral Arterial Disease; Coronary Disease; Collateral Circulation, Any Site

• Registration Number: NCT05043948
• Lead Sponsor: Jung-min Ahn

Brief Summary

The purpose of this study is to evaluate the genome-wide association for the development of collateral circulation for patients with coronary or peripheral artery disease and to develop the molecular genetic treatment model based on genome-wide association data.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-08-21
• Status Verified: 2021-09
• Study First Submitted: 2021-09-12
• Study First Submitted QC: 2021-09-12
• Last Update Submitted: 2021-09-12
• Study First Posted: 2021-09-14
• Last Update Posted: 2021-09-14
• Primary Completion: 2025-06-30
• Study Completion: 2025-12-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 400

Inclusion Criteria

• Age more than 20
• Chronic total occlusive lesion from the coronary or peripheral angiogram

Exclusion Criteria

• Renal dysfunction
• Hepatic dysfunction
• Thrombocythemia or thrombocythemia
• Planned major surgery in 1 year
• History of gastrointestinal haemorrhage
• Malignant tumor

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Correlation between genome and collateral flow	5 years

Trial Locations

Locations (1)

Asan Medical Center; 🇰🇷 Seoul, Korea, Republic of