Comparison of Mephentermine and Norepinephrine infusions for prevention of post-spinal hypotension during elective caesarean delivery:a randomised,double-blind trial.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Effect on umbilical artery pH
研究概览
简要总结
Spinal anesthesia is the preferred technique for elective caesarean section due to rapid onset , ease of administration, and minimal foetal drug exposure. however, one of the most frequent and clinically significant complication is post spinal hypotension, resulting from sympathetic blockade leading to vasodilation and reduced venous return.in pregnant patients it can lead to both maternal and foetal complications therefore its crucial to ensure hemodynamic stability .this thesis emphasis on current strategies to overcome post spinal hypotension with maximal efficacy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 49.00 Year(s)(—)
- 性别
- Female
入选标准
- •Willing to participate, term uncomplicated singleton pregnancy, ASA1 and ASA2 Status, elective caesarean delivery.
排除标准
- •Refusal to participate, emergency c-section,multiple gestation, maternal or fetal disorders, absolute or relative contraindications to spinal anesthesia.
结局指标
主要结局
Effect on umbilical artery pH
时间窗: Post delivery of placenta( at baseline)
次要结局
- Hemodyanamic parameters ( HR SBP DBP MAP SPO2)(APGAR score at 1 & 5 minutes)
研究者
Dr Ananya
Indira Gandhi Institute of Medical Sciences, Patna
