Effects of Levothyroxine on lipid profile in subclinical hypothyroidism
Phase 4
- Conditions
- Subclinicsl Hypothyroidism.Subclinical iodine-deficiency hypothyroidism
- Registration Number
- IRCT138903244179N1
- Lead Sponsor
- Kermanshah University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 90
Inclusion Criteria
High TSH with FT4 in normal range
Exclusion criteria: receiving levothyroxine, glucocorticoids, asprin, amiodaron, lipid lowering agents, OCP, dopamine antagonist eg. metoclopramide or domperidone in 6 months prior to the study, presence of diabetes mellitus, pregnancy, menopause, age older than 60 years
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Triglyceride. Timepoint: Baseline and 3 months after the intervention. Method of measurement: photometery.;Cholestrol. Timepoint: Baseline and 3 months after the intervention. Method of measurement: photometery.;LDL. Timepoint: Baseline and 3 months after the intervention. Method of measurement: photometery.;HDL. Timepoint: Baseline and 3 months after the intervention. Method of measurement: photometery.;Lp(a). Timepoint: Baseline and 3 months after the intervention. Method of measurement: biochemistry.
- Secondary Outcome Measures
Name Time Method TSH. Timepoint: Baseline and 3 months after the intervention. Method of measurement: chemiluminescence.;FT4. Timepoint: Baseline and 3 months after the intervention. Method of measurement: chemiluminescence.