MANAGEMENT OF NUTRITIONAL RICKETS THROUGH AYURVEDA
- Conditions
- Health Condition 1: E550- Rickets, active
- Registration Number
- CTRI/2024/03/064693
- Lead Sponsor
- All India Institute of Ayurveda
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Clinical-—lower limb pains, knock-knees, Delayed eruption and enamel hypoplasia Thorax Rachitic rosary, pigeon chest/pectus carinatum, and Harrison groove.
Biochemical evidence
Serum values of 25-hydroxyvitamin D3- below 30 nmol/L (12 ng/mL) up to 50 nmol/L (20 ng/mL). xxxvii
Radiological findings consistent with the diagnosis of rickets- X-ray wrist and/or knee—widening of the growth plate, generalized osteopenia, metaphysis show cupping, splaying, and fraying.
Documented causes of rickets other than that of nutritional origin rickets.
History of consuming calcium or vitamin D supplements in the preceding six months.
Patients with confirmed or suspected diagnosis of malabsorption or chronic kidney or hepatic disease.
Patients who have underwent steroid treatment for more than 6 months
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Increase in serum 25-hydroxyvitamin D3.Timepoint: 18th day, 55th day, 68th day.
- Secondary Outcome Measures
Name Time Method Increase in Serum Calcium levels. <br/ ><br>Increase in serum Phosphorous levels. <br/ ><br>Changes in Serum ALP values. <br/ ><br>Bone mineral density changes will be assessed through ultrasound bone densitometer if feasible. <br/ ><br>Reduction in scoring of Ayurvedic symptoms- Asthikshaya <br/ ><br>Timepoint: 55th day, 68th day