Do different cardiopulmonary blood flow settings influence perioperative outcome in cardiac surgery patients?

Recruiting

• Conditions: I25.1; I35.0; I35.1; I71.01; I71.05; I71.1; I71.2; I71.9; I25.11; I25.12

• Registration Number: DRKS00034026
• Lead Sponsor: niversitätsklinikum Augsburg

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-05-29
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 1800

Inclusion Criteria

All of the following surgical procedures performed via full sternotomy:
- coronary artery bypass graft [CABG]
- combination procedures (valve reconstruction/ replacement + CABG)
- replacement of the ascending aorta
- type A aortic dissection (Stanford classification)

Exclusion Criteria

- mitral valve replacement or reconstruction
- off pump coronary artery bypass graft
- other valve procedures, that do not fall under the above
mentioned surgical procedures

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
30-day mortality in both groups separated by type of surgical procedure

Secondary Outcome Measures

Name	Time	Method
- intra-/ postoperative catecholamine requirement<br>- length of stay in the ICU and overall<br>- In- hospital mortality and 90- day mortality<br>- ICDSC and SOFA Score<br>- Duration of ventilation and weaning<br>- organ replacement therapy <br>- intra- /postoperative left ventricular ejection fraction<br>- organ failure [acute kidney injury, acute liver injury, ARDS (=acute respiratory distress syndrome)]<br>- postoperative near infrared spectrometry