ow Frequency Ventilation during cardiopulmonary bypass for lung protectio

Not Applicable

Completed

• Conditions: Open-heart surgery with CPB / coronary artery bypass grafting (CABG); Surgery

• Registration Number: ISRCTN34428459
• Lead Sponsor: Imperial College Healthcare NHS Trust (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2012-05-16
• Last Update Posted: 17 October 2016

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

A participant may enter the study if ALL of the following apply:
1. Age =40 and <85 years
2. Undergoing any elective or urgent coronary artery bypass graft (CABG) with cardiopulmonary bypass (CPB) and cardioplegic arrest (CA)
3. Left ventricular ejection fraction >30%

Exclusion Criteria

A participant may not enter the study if ANY of the following apply:
1. Previous pulmonary embolism requiring long term warfarin for =3 months
2. Previous cardiac surgery
3. Current congestive heart failure (NYHA class IV)/cardiogenic shock
4. Chronic renal failure requiring dialysis
5. Emergency or salvage operation
6. On corticosteroid or immunosuppressive treatment
7. Severe chronic obstructive pulmonary disease (COPD), lung pathology and previous radiotherapy
8. Body mass index (BMI) >35

Study & Design

• Study Type: Interventional
• Study Design: Not specified