Effect of intrapulmonary percussive ventilation in non-ventilated patients in intensive care on their oxygenation, lung complications and length of stay compared to standard chest physiotherapy: A randomised controlled trial

Not Applicable

Completed

• Conditions: pulmonary atelectasis,; Pneumonia; Pulmonary consolidation; Respiratory failure; hypoxemia; hypoventilation; Respiratory - Other respiratory disorders / diseases

• Registration Number: ACTRN12619001075178
• Lead Sponsor: epean Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-08-05
• Study Completion: 2022-12-24
• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 106

Inclusion Criteria

Age: adults greater than or equal to 16 years
-FiO2 greater than or equal to 28% via mask or high flow nasal cannula or greater than or equal to 3 litres/minute via nasal cannula
-Evidence of pulmonary atelectasis or consolidation (Confirmed by ICU clinician)
-Patients with SpO2 less than or equal to 90% on room air (RA), respiratory rate (RR) greater than or equal to 25, accessory muscle use (with exception of chronic pulmonary or cardiac condition where a lower SpO2 range is acceptable by the medical team).
-Evidence of sputum retention (based on cough assessment and auscultation findings)

Exclusion Criteria

Intubated patients
-Hypoxemia due to non-respiratory or non-reversible causes such as congestive cardiac failure, low haemoglobin levels, pulmonary hypertension, pulmonary embolism
-Hemodynamic instability; Systolic BP less than or equal to 80 mm Hg, acute myocardial ischemia, ventricular arrhythmia
-FiO2 greater than or equal to 70%
-Pneumothorax (with or without ICC)
-Post esophagectomy / pneumonectomy patients
-Patients with facial fractures/injuries/surgeries
-Frank haemoptysis
-Uncooperative/agitated/confused patients (RASS greater than or equal to +2)
-Drowsy/sedated/unresponsive patients (RASS less than or equal to - 2)
-Pregnant women (pregnant patients in critical care are often not stable and effects of IPV in pregnant patients is unknown)
-Aggressive patients (potential harm to staff members)
-Patients with communication difficulties (NESB) - utilisation of interpreter services twice daily may not be feasible and can be expensive.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ICU Length of stay- This will be recorded in terms of duration (days) participant stayed in ICU. This will be determined by measuring the time of ICU admission to the time when a participant is cleared for the ward by the ICU team (which is usually at the intensivist's discretion during daily morning rounds). <br>The above information will be obtained from the medical records.[ This will be recorded when the participant is cleared from the ICU or when they are transferred out of ICU. This will vary for each participant. <br><br>]