ovel transcatheter arterial embolization for treatment of knee osteoarthritis: a randomized sham-controlled clinical trial - Transcatheter arterial embolization treatment of knee osteoarthritis

Erasmus MC, Universitair Medisch Centrum Rotterdam0 个研究点目标入组 58 人开始时间: 待定最近更新: 2024年4月15日

适应症

试验速览

暂无简介。

•- Age * 18 years
•- Knee pain for a duration of *6 months
•- Knee pain (numeric rating scale *4 - *8) on at least half of the days in the
•preceding month at
•time of inclusion
•- There is insufficient response of conservative treatment for at least 6 months
•- Radiographic knee osteoarthritis (radiographic Kellgren and Lawrence grade

•- Contra-indications for MRI (e.g. metallic foreign bodies, etc.)
•- Contra-indications for angiography
•- Renal insufficiency, checked with blood sample test (GFR < 30 ml/min/1,73 m²);
•- Known allergy to contrast agents;
•- Patient has known allergies to barium sulfate, 3-aminopropyltrialkoxysilane,
•polyphosphazene
•- Women who are pregnant or lactating
•- Intermittent claudication of affected limb
•- Intra articular injections in the ipsilateral knee less than 6 months ago
•- On the waiting list for joint replacement surgery
•- Amitriptyline usage.
•- Insufficient command of the Dutch or English language.
•- Legally incompetent adults.
•- Had previous surgical treatment for knee osteoarthritis (e.g. high tibial
•osteotomy), excluding
•knee arthroscopy
•- Has musculoskeletal co morbidity (e.g. rheumatoid arthritis or gout)
•potentially blurring the
•effect of the treatment.

发起方