The FARINGOCAT study: rapid antigen detection testing in acute pharyngitis

Completed

Conditions: Acute pharyngitis
Respiratory

Registration Number: ISRCTN23587778

Lead Sponsor: Jordi Gol i Gurina Primary Care Research Institute (Institut D'Investigació en Atenció Primària) (IDIAP) (Spain)

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: All

Target Recruitment: 552

Inclusion Criteria

1. Men and women 14 to 60 years old
2. More than one acute pharyngitis symptom, i.e., fever, sore throat, tonsillar exudate, cervical adenopathy and absence of cough, which leads to a visit to the family practice

Exclusion Criteria

1. Does not consent to participate
2. Patient is younger than 14 or older than 60 years old
3. Pharyngitis more than five times in year
4. Immunodepression: quimiotherapy, radiotherapy, active neoplasia, acquired immune deficiency syndrome (AIDS), corticoids, immunosuppressor treatment
5. Valve heart disease
6. Rheumatoid fever
7. Pharyngitis with previous treatment during 15 days or recurrence of symptoms during 4 weeks after 7 days of complete antibiotic treatment
8. Pharyngitis of diphtheria or gonococcica cause
9. Tonsillectomy

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Proportion of inadequate antibiotic prescription in each group<br>2. Use of antibiotic treatment<br>3. Use of rapid antigen detection testing <br>4. Rapid antigen detection testing result<br>5. Culture result<br><br>Outcomes will be measured at baseline and three weeks in all patients. If there is a problem, i.e., a secondary effect, then this may take longer.

Secondary Outcome Measures

Name	Time	Method
1. Clinical symptoms of acute pharyngotonsillitis: fever, tonsillar exudate, cervical adenopathies, absence of cough, measured at baseline and at dates below<br>2. Age, measured at baseline<br>3. Antibiotic treatment, measured at baseline and at dates below<br>4. Specific antibiotic treatment, measured at baseline and at dates below<br>5. Treatment secondary effects, measured at baseline and at dates below<br>6. Days without working, measured at baseline and at dates below<br>7. Medical visits during the first month, measured at week three in all patients, at week four if necessary<br>8. Patient satisfaction, measured between 3 - 4 weeks after the second visit in one group of patients, between 5 - 7 months in another group of patients<br><br>Outcomes will be measured at three weeks in all patients. If there is a problem, i.e., a secondary effect, then this may take longer.