Ghrelin levels in patients with ACNES (Anterior Cutaneous Nerve Entrapment Syndrome) and gastrointestinal complaints, loss of appetite and weight loss.

Recruiting

Conditions: abdominal wall nerve entrapment syndrome
Chronic Abdominal Wall Pain (CAWP)
10000073

Registration Number: NL-OMON52437

Lead Sponsor: Maxima Medisch Centrum

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: Not specified

Target Recruitment: 40

Inclusion Criteria

For the ACNES group
- diagnosed with ACNES
- at least two pseudovisceral complaints including loss of appetite related to
pain and weight loss defined as: unintentional and more than 5% of usual body
weight over at least 6 months
- age between 18 and 65
- receiving treatment for ACNES at our hospital
- obtained written informed consent

For the control group
- age between 18 and 65
- obtained written informed consent

Exclusion Criteria

For the ACNES group
- BMI >= 30 kg/m2
- recent intra-abdominal pathology
- history of bariatric surgery
- endocrine disease
- psychiatric disorder
- can*t obtain adequate follow-up
- pregnancy
- language barrier

For the control group
- BMI >= 30 kg/m2
- ACNES
- weight loss over the last 6 months
- visceral complaints over the last month
- intra-abdominal pathology or surgery
- endocrine disease
- psychiatric disorder
- pregnancy
- language barrier

Study & Design

Study Type: Observational invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameter is the difference in fasting ghrelin blood level<br /><br>between ACNES patients and a healthy control group.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>The difference in fasting ghrelin blood level before and after treatment for<br /><br>ACNES.<br /><br>The difference in fasting ghrelin blood level after treatment for ACNES between<br /><br>the ACNES patients with a successful therapy and those with a failed therapy. </p><br>