Correlation of a predefined set of 96 inflammatory proteins between the serum and intestinal tissue within patients with inflammatory bowel disease
Recruiting
- Conditions
- inflammatory bowel disease
- Registration Number
- NL-OMON22599
- Lead Sponsor
- Academic Medical Center Amsterdam
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 92
Inclusion Criteria
1. Patients ¡Ý 18 years old
2. Diagnosis of IBD, based on a combination of history, physical examination, family history, laboratory tests, endoscopy tests including histopathologic examination of mucosal biopsies, imaging studies and occasionally intraoperative findings
Exclusion Criteria
1. Age < 18 years at inclusion
2. Ongoing use of anticoagulants that may increase the risk of bleeding when biopsies are taken
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess the correlation of protein profiles between intestinal tissue and serum in patients with IBD
- Secondary Outcome Measures
Name Time Method To identify the source matrix that has the highest chance to yield clinically relevant IBD biomarkers in future research<br /><br>To identify putative candidate biomarkers that are able to:<br /><br>o differentiate between IBD and non-IBD controls<br /><br>o differentiate between CD and UC<br /><br>o identify subgroups within the patients groups of CD or UC in alignment with endoscopic severity.<br /><br>To identify possible targets for the future development of therapeutic compounds