Caffeine Versus Placebo for Spinal Headaches

Not Applicable

Completed

• Conditions: Post Dural Puncture Headache
• Interventions: Drug: Caffeine; Drug: saline

• Registration Number: NCT00809627
• Lead Sponsor: United States Naval Medical Center, Portsmouth

Brief Summary

Caffeine will be studied against placebo in patients with positional headache after a lumbar puncture (aka "spinal headache").

Detailed Description

Pain will be assessed at set intervals using a Visual Analog Scale. Blood patch therapy will be offered to all those still in pain at the end of one hour after drug administration.

Study Timeline

• Study Start: 2007-01
• Primary Completion: 2008-05
• Study Completion: 2008-05
• Study First Submitted: 2008-12-16
• Study First Submitted QC: 2008-12-16
• Study First Posted: 2008-12-17
• Status Verified: 2013-10
• Last Update Submitted: 2013-10-28
• Last Update Posted: 2013-10-29

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 21

Inclusion Criteria

• diagnosed with post dural puncture headache

Exclusion Criteria

• age < 18
• pregnant
• allergic to caffeine
• cardiac or peripheral vascular disease
• uncontrolled hypertension

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
1	Caffeine	IV caffeine with saline and opiate
2	saline	IV saline with opiate

Primary Outcome Measures

Name	Time	Method
Pain as measured by Visual Analog Scale	60 minutes

Trial Locations

Locations (1)

Emergency Department, Naval Medical Center Portsmouth; 🇺🇸 Portsmouth, Virginia, United States