A Comparison Between Two Strategies for Postpartum Anemia Diagnosis and Follow up After Vaginal Deliveries
- Conditions
- Postpartum Anemia
- Interventions
- Other: Monitoring hemoglobin levels to detect anemia by screening of women at increased risk for post partum anemiaOther: Monitoring hemoglobin levels following anemia associated symptoms
- Registration Number
- NCT02434653
- Lead Sponsor
- HaEmek Medical Center, Israel
- Brief Summary
Anemia diagnosis by hemoglobin level monitoring in women after vaginal delivery by symptoms versus screening of women at increased risk for post-partum anemia.
- Detailed Description
Anemia is common following delivery. It is associated with some serious complications including increased risk for syncope and in severe cases even cardiogenic shock. Yet, anemia-associated symptoms might manifest relatively late after the patient have lost a fair amount of blood, which was not diagnosed early enough. To date, there are not acceptable guidelines for monitoring hemoglobin levels after delivery. Theoretically, there are 2 approaches for hemoglobin monitoring - one by taking hemoglobin levels in order to diagnose anemia in patients reporting anemia-associated symptoms. The other approach is by screening of women at increased risk for post-partum anemia. In the present study we aimed to compare those 2 approaches.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 1679
- pregnant women after vaginal delivery
- pregnant women with known sensitivity to the product iron sucrose
- pregnant women after cesarean section
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Postpartum anemia diagnosis following patients screening Monitoring hemoglobin levels to detect anemia by screening of women at increased risk for post partum anemia Post partum anemia will be assessed by taking hemoglobin level in patients at increased risk to develop post-partum anemia in the first 5 days following delivery, defined as patients with initial (before or immediately after delivery) hemoglobin level of 10.5 g/dl or less regardless of symptoms, or in cases of severe post partum hemorrhage. Postpartum anemia diagnosis following symptoms Monitoring hemoglobin levels following anemia associated symptoms Post partum anemia will be assessed by taking hemoglobin level following symptoms consistent with anemia, severe postpartum hemorrhage or hemoglobin level below 8 g/dL in the first 5 days following delivery
- Primary Outcome Measures
Name Time Method The rate of patients diagnosed with anemia Up to 3 days postpartum Hemoglobin of 10 g/dl or below
The rate of patients who received treatment with intravenous iron sucrose Up to 3 days postpartum
- Secondary Outcome Measures
Name Time Method The rate of patients who received blood transfusion From delivery and up to 5 days The rate of women with post-partum hemorrhage From delivery and up to 5 days The rate of women who underwent uterine revision following delivery after their arrival to the maternity ward From delivery and up to 5 days The rate of women who needed uterotonic agents after their arrival to the maternity ward From delivery and up to 5 days The average blood tests number that was performed From delivery and up to 5 days Minimal and average hemoglobin level From delivery and up to 5 days The composite symptoms of anemia and functional capacity after 6 weeks postpartum as assessed by a questionnaire 6 weeks postpartum Each question in the questionnaire will receive a score. The total score will be reported.
Hemoglobin level 6 weeks postpartum 6 weeks postpartum
Trial Locations
- Locations (1)
Haemek Medical Center
🇮🇱Afula, Israel