Elderly With Hip Fracture and Perioperative Hemoglobin and Perfusion Index Levels

Completed

• Conditions: Delirium; Anemia
• Interventions: Procedure: Surgery for hip fracture

• Registration Number: NCT02838706
• Lead Sponsor: Hvidovre University Hospital

Brief Summary

The overall aim of the study is to investigate the time difference in the diagnosing of anemia among elderly with hip fracture, between measurements with standard blood samples and non-invasive SpHb-measuring. Another aim is to investigate the relationship between perfusion index and prolong perioperative anemia and the potential impact on perioperative complications.

Detailed Description

Immediately after admission and diagnosis of a hip fracture the patients will be monitored with Masimo SpHb. The Patients will be continuously measured until the third day after surgery. The Monitors Hb and PI data but not the SpO2% will be blinded to all participating healthcare personnel.The first three postopertive days the patiens will daily be examined to determined it they have developed delirium.

All perioperativ complications in that period will be monitored.

Study Timeline

• Study First Submitted: 2016-04-18
• Study Start: 2016-05
• Study First Submitted QC: 2016-07-15
• Study First Posted: 2016-07-20
• Primary Completion: 2016-11
• Study Completion: 2016-12-01
• Status Verified: 2017-04
• Last Update Submitted: 2017-04-25
• Last Update Posted: 2017-04-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• Age ≥ 65 years
• Primary hip fracture requiring surgery
• Patients able to give informed consent
• Patients who are able to undergo the Hospitals standardized fast track
• Perioperative care regimen for hip fracture including are pre operative placed epidural

Exclusion Criteria

• Patients who can not co-operate to have a sensor attach to the finger continuous for 4 days.
• Patients who has allergy to the bandage that is used to attach the sensor.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Elderly with hip fracture	Surgery for hip fracture	The subjects are patients age ≥ 65 years requiring surgery for a hip fracture

Primary Outcome Measures

Name	Time	Method
Delay in diagnosting perioperative anemia	From admission up to and including the 3 postopertive day	Description of lag time between detection of anaemia by SpHb and Hb by blood sampling/transfusion
Perfusion index, periopertive anemia and delirium	From admission up to and including the 3 postopertive day	The relation between average perioperative perfusion index, cumulated perioperative anemia over time and patient outcome in the form of medical complications, mortality, delirium and LOS.

Secondary Outcome Measures

Name	Time	Method
Perfusion index as a predictor of early warning score (EWS)	From admission up to and including the 3 postopertive day	Is there a relationship between low perfusion index an high EWS?

Trial Locations

Locations (1)

Copenhagen University Hospital Hvidovre, department of anesthesiology; 🇩🇰 Hvidovre, Denmark