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RSSearch Patient Registry-Long Term Study of Use of SRS/SBRT

Recruiting
Conditions
Neoplasms
Arteriovenous Malformation of Central Nervous System
Trigeminal Neuralgia
Interventions
Radiation: SRS/SBRT
Registration Number
NCT01885299
Lead Sponsor
The Radiosurgery Society
Brief Summary

The RSSearch® Registry is an international multi-year database designed to track SRS/SBRT (Stereotactic Radiosurgery/Stereotactic Body Radiation Therapy) utilization, treatment practices and outcomes to help determine, over time, the most effective use of these systems in management of patients with life threatening tumors and other diseases. (This study was formally called ReCKord and included the CyberKnife only; The ReCKord study continues as a CyberKnife subset of RSSearch.)

Detailed Description

The Registry is designed to help SRS/SBRT (Stereotactic Radiosurgery/Stereotactic Body Radiation Therapy) users to understand utilization of and key treatment outcomes for these treatment approaches. Some of the objectives include:

Allow participants to record information about usage of SRS/SBRT in everyday practice, including patient characteristics and disease information, treatment plans and outcomes Provide participants with ready access to data for publication of their own experience and as a tool for establishing collaborations with other participating sites Facilitate quality improvement efforts for individual treatment providers Understand the effectiveness of different treatment plans for different types of lesions, diseases and treatments

The Registry tracks select outcomes for each condition treated by SRS/SBRT (for example, PSA for prostate cancer); the Registry also provides individual participants the ability to add additional outcomes for each and any condition of specific interest to their institutions.

The Registry is hosted by Vision Tree, Inc who is an independent vendor of electronic registries; they are responsible for HIPAA compliance, including all security mechanisms.

Patients will be enrolled prospectively. Some retrospective patient data is likely to be included in order to capture both short and longer term outcomes data.

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
50000
Inclusion Criteria
  • Diagnosis of benign or malignant tumors or other conditions deemed treatable by stereotactic radiosurgery or stereotactic body radiotherapy
  • Willingness to sign an Informed Consent Document or verbally agree to participation
Exclusion Criteria
  • There are no specific exclusion criteria, but patients who are unwilling to sign the ICD or who decline participation will not be included

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Patients being treated by SRS/SBRTSRS/SBRTPatients with a condition being considered for treatment by SRS/SBRT
Primary Outcome Measures
NameTimeMethod
Overall survivalUp to 5 years

Survival from time of treatment to death

Secondary Outcome Measures
NameTimeMethod
Local and distant recurrenceOne to Five years

Calculated from time of treatment to recurrence

Trial Locations

Locations (13)

Penrose Cancer Center

🇺🇸

Colorado Springs, Colorado, United States

Sylvester Comprehensive Cancer Center, University of Miami

🇺🇸

Miami, Florida, United States

Southeast Georgia Health System

🇺🇸

Brunswick, Georgia, United States

Henry Ford Health System

🇺🇸

Detroit, Michigan, United States

AtlantiCare Regional Medical Center and AtlantiCare Cancer Care Institute

🇺🇸

Egg Harbor Township, New Jersey, United States

Riverview Medical Center

🇺🇸

Red Bank, New Jersey, United States

NJ Cyberknife at Community Medical Center

🇺🇸

Toms River, New Jersey, United States

Montefiore Medical Center

🇺🇸

Bronx, New York, United States

Geisinger Health System

🇺🇸

Danville, Pennsylvania, United States

Philadelphia CyberKnife

🇺🇸

Philadelphia, Pennsylvania, United States

Pottstown Memorial Medical Center

🇺🇸

Pottstown, Pennsylvania, United States

Cyberknife at Erlanger

🇺🇸

Chattanooga, Tennessee, United States

St. Mary's Medical Center

🇺🇸

Huntington, West Virginia, United States

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