Estimated Glomerular Filtration Rate After Kidney Transplantation - the Formula MDRD, CKD-EPI or Cockroft-Gault?

Completed

• Conditions: Renal Function Disorder
• Interventions: Other: Estimating of formula MDRD, CKD-EPI, Cockroft-Gault,; Device: Tanita BC 418- Bioelectrical impedance analysis

• Registration Number: NCT02443363
• Lead Sponsor: Medical University of Warsaw

Brief Summary

The study included 300 patients who are post-kidney transplantation (\> 3 months and \<10 years). An analysis of body composition using bioelectrical impedance, calculated BMI and serum creatinine was determined. Glomerular filtration rate (GFR) was calculated using the formula CKD-EPI, Modification of Diet in Renal Disease (MDRD) and Cockroft-Gault.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-04
• Study First Submitted: 2015-05-10
• Study First Submitted QC: 2015-05-10
• Study First Posted: 2015-05-13
• Status Verified: 2015-09
• Primary Completion: 2015-09
• Study Completion: 2015-09
• Last Update Submitted: 2015-09-30
• Last Update Posted: 2015-10-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 170

Inclusion Criteria

• give voluntary consent to participate in the study
• functioning graft longer than 3 months to 10 years
• no clinical cardiovascular disease during the 6 months preceding entry
• stable graft function- glomerular filtration rate > 30 ml/min/1.73 m2, creatinine concentration <2.5 mg/dl

Exclusion Criteria

• not meet the above criteria
• episode of illness (for example: infection)
• pregnancy

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Patients After Kidney Transplantation	Estimating of formula MDRD, CKD-EPI, Cockroft-Gault,	A total of 300 consecutive patients admitted to routine visit in Transplant Centre with functioning graft longer than 3 months to 10 years
Patients After Kidney Transplantation	Tanita BC 418- Bioelectrical impedance analysis	A total of 300 consecutive patients admitted to routine visit in Transplant Centre with functioning graft longer than 3 months to 10 years

Primary Outcome Measures

Name	Time	Method
Differences in estimating GFR using formula MDRD, CKD-EPI and Cockroft-Gault in short and long-term postoperative period.	1 day

Trial Locations

Locations (1)

Medical University of Warsaw; 🇵🇱 Warsaw, Mazovian, Poland