EUCTR2014-000763-41-ES进行中（未招募）1 期
Study of genetic Alzheimer?s disease mutation carriers in preclinical stages of the disease: 18F-Florbetaben Positron Emission Tomography study.
FUNDACIÓ CLÍNIC PER A LA RECERCA BIOMÈDICA0 个研究点目标入组 40 人开始时间: 2014年7月22日最近更新:
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
入选标准
- •1. Adult children (> 18 yo) of genetic Alzheimer?s disease
- •patients with a known mutation in PSEN1, APP o PSEN2
- •genes and who are either cognitively normal (CDR=0) or
- •have mild symptoms of cognitive decline (CDR 0.5 or 1)
- •2. According to the principal investigator, participants must
- •be committed to participate and complete all study
- •procedures.
- •3. Has signed the Informed Consent Form voluntarily to
- •participate in the study
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 40
- •F.1.3 Elderly (>=65 years) no
- •F.1.3.1 Number of subjects for this age range
排除标准
- •1. Subjects that are not able to complete the study.
- •2. Any major disease or history of a major disease,
- •especially hepatobilliar disease (AST /ALT ? 5 x ULN) or
- •advanced renal insufficiency (creatinine ? 2 x ULN)
- •3. Current or previous history of alcohol abuse or epilepsy
- •4. Allergic to Florbetaben or any of its constituents
- •5. Multiple drug allergies and/or previous history of contrast
- •6. Pregnancy or breast feeding or planned pregnancy during
- •the study period
- •7. Any disease or history of disease which, in the opinion of
- •the investigator, can cause disturbance of brain function
- •(e.g. vitamin B12 or folic acid deficiency, disturbed
- •thyroid function)
- •8. Evidence for any other neurological or psychiatric disease
研究者
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