EUCTR2014-000763-41-ES
Active, not recruiting
Phase 1
Study of genetic Alzheimer?s disease mutation carriers in preclinical stages of the disease: 18F-Florbetaben Positron Emission Tomography study.
FUNDACIÓ CLÍNIC PER A LA RECERCA BIOMÈDICA0 sites40 target enrollmentJuly 22, 2014
DrugsNeuraceq
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- FUNDACIÓ CLÍNIC PER A LA RECERCA BIOMÈDICA
- Enrollment
- 40
- Status
- Active, not recruiting
- Last Updated
- 7 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Adult children (\> 18 yo) of genetic Alzheimer?s disease
- •patients with a known mutation in PSEN1, APP o PSEN2
- •genes and who are either cognitively normal (CDR\=0\) or
- •have mild symptoms of cognitive decline (CDR 0\.5 or 1\)
- •2\. According to the principal investigator, participants must
- •be committed to participate and complete all study
- •procedures.
- •3\. Has signed the Informed Consent Form voluntarily to
- •participate in the study
- •Are the trial subjects under 18? no
Exclusion Criteria
- •1\. Subjects that are not able to complete the study.
- •2\. Any major disease or history of a major disease,
- •especially hepatobilliar disease (AST /ALT ? 5 x ULN) or
- •advanced renal insufficiency (creatinine ? 2 x ULN)
- •3\. Current or previous history of alcohol abuse or epilepsy
- •4\. Allergic to Florbetaben or any of its constituents
- •5\. Multiple drug allergies and/or previous history of contrast
- •6\. Pregnancy or breast feeding or planned pregnancy during
- •the study period
- •7\. Any disease or history of disease which, in the opinion of
Outcomes
Primary Outcomes
Not specified
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