MedPath

ocal Use of Antibiotic Powder during total knee replacement

Not Applicable
Completed
Conditions
Health Condition 1: M179- Osteoarthritis of knee, unspecifiedHealth Condition 2: M171- Unilateral primary osteoarthritisof knee
Registration Number
CTRI/2021/02/031310
Lead Sponsor
Sunshine Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
100
Inclusion Criteria

All adult patients undergoing primary total knee arthroplasty for osteoarthritis of the knee joint

Exclusion Criteria

Inflammatory arthritis

Post-traumatic arthritis

Previous knee surgery

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Acute infection rate: Incidence of Surgical Site Infections (SSI) or Periprosthetic Joint Infection (PJI)Timepoint: Assessment and documentation of surgical site infection (SSI) or Peri-prosthetic Joint Infection (PJI) at 2 weeks, 4 weeks, 3 months, 6 months, 1 year after surgery
Secondary Outcome Measures
NameTimeMethod
Correlation of patient factors with infection ratesTimepoint: 6 months and 1 year;Functional outcome assessed by Oxford Knee Score (OKS)Timepoint: 3 months, 6 months, 1 year;Functional outcomes assessment by Patient reported outcome measure (PROM) by Forgotten Joint Score (FJS)Timepoint: 3 months, 6 months, 1 year;Functional outcomes using WOMAC scoreTimepoint: 3 months, 6 months, 1 year;Long term Infection rateTimepoint: 1 year;Quality of Life Indicator (EQ-5D)Timepoint: 3 months, 6 months, 1 year
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