The efficacy of local vancomycin on postoperative infectio
Phase 3
- Conditions
- Surgical site infections.Infection and inflammatory reaction due to internal fixation device [any site]T84.6
- Registration Number
- IRCT20210712051848N1
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 360
Inclusion Criteria
All patients over 18 years of age who underwent open spinal surgery in the cervical, thoracic and lumbosacral regions
Exclusion Criteria
Previous history of spine infection
History of immunodeficiency or ongoing chemotherapy
History of kidney or liver failure
Allergy to vancomycin or cephalosporin
Inability to follow up to 3 months after surgery
Primary or metastatic spinal cord or spine tumors
Dissatisfaction with the study.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Discharge from the wound. Timepoint: The wound site is examined at the time of discharge, two weeks after surgery, and 3 months after surgery. Method of measurement: Physical examination and history.;Swelling of the operation site. Timepoint: The wound site is examined at the time of discharge, two weeks after surgery, and 3 months after surgery. Method of measurement: Physical examination and history.;Redness of the operation site. Timepoint: The wound site is examined at the time of discharge, two weeks after surgery, and 3 months after surgery. Method of measurement: Physical examination and history.
- Secondary Outcome Measures
Name Time Method