Experiment of effectiveness of local administration of an antibiotic named Vancomycin at sternal wound for prevention of wound infection after coronary bypass surgery.
Phase 4
- Conditions
- Health Condition 1: I251- Atherosclerotic heart disease of native coronary arteryHealth Condition 2: null- Sternotomy wound infection
- Registration Number
- CTRI/2018/08/015382
- Lead Sponsor
- Department of Anaesthesiology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
UNDERGOING OFF PUMP CORONARY ARTERY BYPASS SURGERY.
Exclusion Criteria
CHRONIC KIDNEY DISEASE(pre-op Serum creatinine more than 2mg/dl or 177microMol/liter.
Obesity(BMI more than 30kg/m2).
Malnourished(BMI less than 18.5kg/m2).
LOCAL SKIN INFECTION.
EMERGENCY SURGERY,RE-EXPLORATION OR RE-DO SURGERY.
BILATERAL INTERNAL MAMMARY ARTERY GRAFTING.
ALLERGIC TO VANCOMYCIN.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method REDUCTION OF STERNAL WOUND INFECTIONTimepoint: AFTER THREE MONTHS FROM DATE OF SURGERY.
- Secondary Outcome Measures
Name Time Method REDUCTION OF TIME OF MECHANICAL VENTILATION DEPENDENCY AND REDUCED HOSPITAL STAY.Timepoint: TIME OF EXTUBATION AT ITU AND TIME OF DISCHARGE FROM HOSPITAL.