Effect of Vancomycin as antibiotic lock technique in prevention of catheter associated infection in stem cell transplantation patientsV
Phase 2
- Conditions
- catheter- related Blood stream infection (CRBSI).Streptococcus, Staphylococcus, and Enterococcus as the cause of diseases classified elsewhere
- Registration Number
- IRCT20100127003210N18
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
All of patients undergoing HSCT whom non-tunneled CVC (arrow) will be inserted newly.
Exclusion Criteria
Hypersensivity to Vancomycin
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Fever, erythema, purulence (catheter exit site), swelling. Timepoint: observe for 21 days from catheterization. Method of measurement: clinical examination, thermometer.;Infection. Timepoint: observe for 21 days from catheterization. Method of measurement: Blood culture (peripheral, catheter).
- Secondary Outcome Measures
Name Time Method WBC and Platelet engraftment. Timepoint: start of antibiotic lock until 21 days after. Method of measurement: CBC.;Hospitalization time. Timepoint: from day of antibiotic lock until hospital clearance. Method of measurement: Day count.