Evaluation of the effect of vancomycin and betadine on wound infectio

Not Applicable

Recruiting

• Conditions: Open Fractures in Limbs.; Injury of unspecified body region; T14.8

• Registration Number: IRCT20211023052845N1
• Lead Sponsor: Esfahan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 11 January 2022

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Diagnosis of open fracture and the need for open reduction and internal fixation surgery
The patient should not be referred to the operating room as a vital emergency and should be fasted for 8 hours before the operation
Age between 18 and 65 years
Having a body mass index between 18 and 25
Not pregnant during the study
Lack of sensitivity to seafood
No autoimmune diseases and immune system defects (Guillain-Barre, multiple sclerosis, immune deficiency syndrome, etc.)
Not having any declining bone disease
Do not take antibiotics one week before surgery
No skin diseases
No history of orthopedic and neurosurgery during the last 6 months
Absence of cIII degree open fractures in Gastillo Anderson classification
No smoking and drug addiction
Lack of underlying and autoimmune diseases (diabetes, multiple sclerosis, immune deficiency syndrome, etc.)
No previous allergy to antibiotics and disinfectants
Informed consent

Exclusion Criteria

Intraoperative blood transfusion
Unforeseen events before surgery such as cardiac arrest and death
Patient death during study (within 30 days after surgery)
Bleeding more than 200 cc
Duration of surgery more than 2 hours
Arbitrary use of antibiotics without a doctor's prescription
The interval between going to the emergency room and surgery is more than 23 hours
Reluctance to continue participating in research

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Infection. Timepoint: The first, second, fourteenth and twenty-eighth days after surgery. Method of measurement: Visual scale analog and laboratory sampling.