The influence of electroencephalographic density spectral array guidance of sevoflurane administration on recovery from general anaesthesia in children between 6 months and 12 years.
Completed
- Conditions
- n.v.t.10009720
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 112
Inclusion Criteria
Written informed consent of the parents/legal representatives
Age > 6 months and < 12 years
Surgical procedure requiring general anaesthesia supplemented with caudal
analgesia
Ability of the parents or legal guardians to communicate in Dutch
Exclusion Criteria
Withdrawal of informed consent
(Chronic) use of drugs influencing the electroencephalogram
Use of premedication
Known intolerance for sevoflurane
Parents/legal guardians unable to communicate in Dutch
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>the influence of density spectral array monitoring with the Narcotrend monitor<br /><br>on the speed of emergence from general anaesthesia with sevoflurane. The speed<br /><br>of emergence is defined as the time interval between the end of hypnotic drug<br /><br>application and the moment when discharge criteria from the operating room are<br /><br>met (defined as a Steward score >= 3).</p><br>
- Secondary Outcome Measures
Name Time Method <p>Total time from discontinuation of anaesthetic drug delivery until discharge<br /><br>from the post anaesthesia care unit.<br /><br><br /><br>The difference in intra-operative blood pressure between the intervention group<br /><br>and the control group.<br /><br><br /><br>Differences of depth of hypnosis during the procedure, as measured by the<br /><br>Narcotrend monitorTM.<br /><br><br /><br>The incidence of postoperative delirium by the Cornell Assessment of<br /><br>Postoperative Delirium (CAPD) score<br /><br><br /><br>Incidence of recall of events during the procedure (awareness)<br /><br><br /><br>Adverse events </p><br>