Optimal dose of Dexmedetomidine added to 0.2 percent Ropivacaine in Caudal Block for post operative analgesia in paediatric patients: a randomised prospective controlled study
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 入组人数
- 75
- 试验地点
- 1
- 主要终点
- To record the time of requirement of first rescue
研究概览
简要总结
Pediatric patients require specific attention when it comes to postoperative analgesia and caudal block as a central nerve block technique, is one of the common methods performed to manage perioperative pain in pediatric lower abdominal and perineal surgeries. Local anesthetics have usually been the main drug in such cases, and if administered alone in the caudal blockade, they do not usually provide prolonged analgesia. Ropivacaine is one of the most common drugs in this group. The addition of dexmedetomidine to local anesthetics or its administration as an adjunct for pain management in a variety of techniques enhances their effects. This study will be carried out to compare the efficacy of ropivacaine with different doses of dexmedetomidine in caudal block for pediatric lower abdominal and perineal surgeries.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 2.00 Year(s) 至 6.00 Year(s)（—）
- 性别
- All
入选标准
- •Assessed patients of ASA physical status I and II.
- •Normal biochemical and hematological parameters.
- •Age group between 2-6 years.
- •Lower abdominal and perineal surgeries, lasting one to three hours under general anaesthesia f.
- •Informed written conset from legal guardian.
排除标准
- •Parent/legal guardian not willing b.
- •Sacral abnormalities c.
- •Patients with coagulopathies d.
- •History of allergy to study drug.
结局指标
主要结局
To record the time of requirement of first rescue
时间窗: Visual Analogue Scale Score | Just after extubation | 1hours post surgery | 2hours post surgery | 6hours post surgery | 12hours post surgery | 24hours post surgery
analgesic
时间窗: Visual Analogue Scale Score | Just after extubation | 1hours post surgery | 2hours post surgery | 6hours post surgery | 12hours post surgery | 24hours post surgery
次要结局
- a) To record the hemodynamic parameters systolic blood pressure, diastolic blood pressure, heart rate and MAP(b) To record incidence of adverse effects i.e. hypotension, bradycardia and sedation)