Evaluation of muscle relaxation effect of rocuronium in neonates for emergency surgery
Not Applicable
- Conditions
- Health Condition 1: R688- Other general symptoms and signsHealth Condition 2: K318- Other specified diseases of stomach and duodenumHealth Condition 3: J988- Other specified respiratory disorders
- Registration Number
- CTRI/2021/11/038229
- Lead Sponsor
- Vardhman Mahavir Medical College
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Term neonates (0-1 month of age), American Society of Anesthesiologists (ASA) Grade 1 and 2, of either sex, undergoing emergency surgery under general anaesthesia requiring orotracheal intubation
Exclusion Criteria
1.Neonates with anticipated difficult airway
2.Congenital syndromes involving head, neck and cardiovascular system
3.Raised intracranial pressure
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate intubating conditions with rocuronium(0.45mg/kg) in neonates and compare it with succinylcholine (2mg/kg)Timepoint: Assessment of intubating conditions will be done at the time of intubation using the Goldberg scale
- Secondary Outcome Measures
Name Time Method To evaluate recovery time with rocuronium (0.45mg/kg) in neonates at the end of surgeryTimepoint: Recovery time will be measured by time to reversal and time to extubation. <br/ ><br>Time to reversal: Last skin suture to administration of reversal agents. <br/ ><br>time to extubation: Last skin suture to time of extubation. <br/ ><br>Neuro-muscular monitoring and time to achieve TOF ratio greater than 0.7, TOF ratio greater than 0.9 after skin closure will also be noted. <br/ ><br>